Sema4 Elements®

Expanded Carrier

Why choose Sema4 Elements® Expanded Carrier Screen?

With one of the most comprehensive and accurate carrier screens available, we are committed to helping patients make informed family planning decisions for a healthier future.

If you are pregnant or planning for pregnancy, our Expanded Carrier Screen with Personalized Residual Risk is designed to give you a comprehensive and accurate understanding of your likelihood of passing a genetic condition onto your child.

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With a simple blood or saliva test, find out if you and your partner are carriers of genetic variants (or changes) that could affect your children.


When assessing risk, precision matters. Sema4 Elements® ECS uses advanced sequencing technologies that are >99% accurate.

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Sema4 Elements® ECS can identify ancestry information from your DNA, which is used to calculate personalized residual risk.

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Screens for up to 502 genes to give you the information you need to plan for a healthier future for your family.

Learn how one couple’s genetic testing results from Sema4 made finding the right donor even more critical in making informed decisions for their future family.

How does it work?

Get started. Talk to your doctor about requesting the screen.

Your doctor takes a single blood draw or saliva sample and sends it to our lab. Saliva tests can also be taken at home.

Your sample is analyzed by our state-of-the-art sequencing technologies. This usually takes about 2 weeks.

Once your genetic screen is completed, a genetic counselor may contact you to explain your results and answer any questions you might have.

If your Provider has chosen Couples Reporting, both members of the couple will have the ability to view each other’s clinical information in reports and genetic counseling sessions.*

Medical experts recommend carrier screening
Medical experts, such as the American College of Obstetricians and Gynecologists, recommend that carrier screening be offered to all women who are pregnant or planning for pregnancy.

Watch our Carrier Screening Pre-test Video

Your healthcare provider may have discussed the option of genetic carrier screening with you. The purpose of genetic carrier screening is to determine if a reproductive couple may be at increased risk of having a child affected with a genetic condition. Watch this informational video to learn more about genetics and the possible outcomes of carrier screening.

Pregnancy Journey

As a Sema4 Elements®ECS patient, you will have access to an interactive educational resource in our Patient Portal called Pregnancy Journey. Learn more.

Patient Perspectives


Looking to register your Saliva Kit?
Registration of your Carrier Screening Saliva Kit is no longer necessary due to our upgraded tracking system. Please continue to the next step listed on your instruction sheet.

Questions? We’re here to help.

Kindly fill out the form below and we’ll schedule a time to discuss your needs. Or feel free to call us at 800-298-6470.

*Genetic carrier screening is used to determine if reproductive partners may be at increased risk of having a child affected with a genetic condition. Reproductive partners’ information is generally analyzed in pairs to better determine clinically significant results and actionable measures.  If your Provider has chosen to receive a single comprehensive report that analyzes both reproductive partners’ information (a “Couples Report”), Sema4 will disclose to each partner the other partner’s clinical information during genetic counseling sessions, and will provide genetic counseling session notes and a report that contains both partners’ clinical information to each partner and their healthcare providers. The sharing of clinical information between partners and family members is covered in Sema4’s informed consent forms, which can be found on our Resources webpage.