Meet Sema4

Sema4 is a patient-centered health intelligence company dedicated to advancing the diagnosis, treatment, and prevention of disease. With Centrellis™, our innovative health intelligence platform, we’re using advanced network analysis to build better models of human health and deliver personalized insights for patients.

Why Sema4 Expanded Carrier Screen?

Clinically Broad
  • We offer the most overall comprehensive and accurate Expanded Carrier Screen (ECS) in the industry that screens for more than 280 genetic diseases
  • Easily customizable to address specific clinical needs
  • Includes 101 genes associated with Jewish founder mutations for comprehensive coverage for patients with Jewish ancestry
  • State-of-the-art technology that utilizes a next-generation sequencing (NGS) platform
Commitment to patient and provider experience
  • Dedicated Customer Success Team and personalized services to seamlessly align with your practice workflow
  • Digital tools, such as the Sema4 provider portal, to make it easy for you to order and review test results, access detailed test information, and interface with your EMR
  • Patients can track their tests, view results, and access educational materials through the Sema4 patient portal
  • Proactive genetic counseling services for your patients and practice to offer education assistance interpreting results, and guidance on care options
Support for patients and providers
  • In-network with the majority of national and regional insurers
  • Dedicated to helping providers and patients navigate the billing landscape, with pre-authorization services for providers and benefits investigation services for patients
  • Patient-friendly billing policies, including competitive self-pay prices and financial assistance programs

Contact Us

Thank you for your interest in Sema4. We are eager to connect with you. Please submit this quick form and one of our representatives will contact you to answer questions.

Are you a:

First name:

Last name:

Email address:


Practice name:

Practice zip code:


Additional information or comments:

Feel free to review our Terms of Use and Privacy Policy

Want to learn more?

To learn more about our carrier screening services, call 844‑683‑6220 today or schedule a time that works best for you. Our client service associates are available 5 days a week, Monday-Friday 8:00 a.m. to 8:00 p.m. EST.