Support throughout your hereditary cancer testing process


At Sema4, we believe that knowledge is power. We are here to help you understand what your genetic information means for you and your family members.


What could a positive test result mean?


A positive result means that testing identified at least one harmful genetic change in a gene that is associated with increased risk for developing cancer. Such genetic changes are referred to as a pathogenic or likely pathogenic variant on your genetic test report. In some cases, an individual who only has one pathogenic or likely pathogenic variant in a gene is not expected to have an increased risk of developing cancer.

The type of cancer, level of risks, and medical management recommendations will depend on your specific genetic test result.

Why does sharing my genetic test result with family members matter?

If your test result is positive, genetic testing may be indicated for your family members to determine if they carry the same pathogenic variant as you. Your test result is a piece of powerful information that can help both you and your family understand cancer risks. Your test result can also help you and your family members make informed healthcare decisions with appropriate healthcare providers.

Starting the conversation about genetic testing with your family members can help them understand the importance of this information. In some cases, your family members’ genetic test result may enable them to take steps to reduce their cancer risk or detect cancer at an earlier, more treatable stage.
Sharing this type of information is important, but keep in mind that your relatives’ views about health and cancer may differ from your own.



Next Steps to Consider:


– Think about which family members you would like to share your results with (i.e., biological relatives)

– Download a sample letter to a family member. View here

– Give them a copy of your test results and share this link so they can learn more about hereditary cancer genetic testing

Learn more about Family Variant Testing



Additional Resources:


– To find a genetic counselor, visit

– National Cancer Institute

– Genetic Information Nondiscrimination Act (GINA) 


Still have questions?

Kindly fill out the form below and we’ll schedule a time to discuss your needs. Or feel free to call us at 800-298-6470.