Advanced molecular profiling technologies

 

Sema4 Signal WES/WTS and Sema4 Signal PanCancer integrate tumor-normal matched WES with WTS to deliver the most comprehensive molecular insights:

      • Hybrid capture-based next generation sequencing of 18,500 genes

 

      • Run on the Illumina NovaSeq 6000 system in our CLIA-certified, CAP-accredited lab

 

      • Reporting of:

        • SNVs, In/Dels
        • CNVs
        • Arm and whole chromosome aneuploidies
        • Gene fusions (RNA)
        • Spice variants (RNA)

 

      • Assessment of:

        • TMB
        • MSI
        • PD-L1 antibodies 22C3 and SP142

 

      • Tumor-normal sequencing to enable differentiation between somatic and germline alterations

 

      • Target sequencing depth:

        • Tumor: 250X
        • Normal: 100X
        • RNA: 100M reads

 

View Validation Summary

 

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Feel free to call us at 833-486-6260 or fill out the form below and we’ll schedule a time to discuss your needs.