Rong Chen, Ph.D., an expert in translational bioinformatics, has published more than 80 papers in journals such as Nature Biotechnology and The Lancet. Rong has developed novel methods to predict personal disease risk by integrating genome sequencing, electronic medical records, and environmental factors.
Before joining Sema4, Rong was an Assistant Professor in the Department of Genetics & Genomic Sciences and Institute of Genomics & Multiscale Biology, and Director of the Clinical Genome Informatics Laboratory at Icahn School of Medicine at Mount Sinai.
Rong received his B.S. in Chemical Physics from the University of Science and Technology in China, his M.S. in Structural Biology from the Chinese Academy of Sciences, and his Ph.D. in Bioinformatics from Boston University.
Chief Medical Officer – Reproductive Health
In addition to serving as Chief Medical Officer – Reproductive Health at Sema4, Alan B. Copperman, M.D., is co-founder and a Medical Director of RMA of New York, one of the country’s largest and most prestigious IVF centers. He also serves as the Director of the Division of Reproductive Endocrinology & Infertility and the Vice-Chairman of the Department of Obstetrics, Gynecology & Reproductive Science at Icahn School of Medicine at Mount Sinai.
Alan has published numerous papers, book chapters, and abstracts on reproductive medicine and frequently features in print, digital media, and local and national news shows. He has been named to New York Magazine’s list of Best Doctors for 16 years in a row and has been recognized annually by Castle Connolly and SuperDocs as one of the top fertility doctors.
Chief Analytics Officer
In his role as Chief Analytics Officer, Krish Ghosh, Ph.D., is driving the growth of Sema4 through the development of next-generation software products, big data analytics, innovative clinical trial optimization solutions, and strategic partnerships with companies with data, technology, and analytical capabilities.
Krish has more than 25 years of experience developing and executing business strategies and leading cross-functional global teams and programs to drive growth for companies in the pharmaceutical, healthcare, and clinical research organization industries. He also has broad expertise with the applications of artificial intelligence, machine learning, and natural language processing tools to develop industry-leading capabilities in clinical trial management and conduct.
Krish received his Ph.D. in Statistics and MBA in Finance from Temple University.
Head of Statistical Genomics
Ke Hao, Sc.D., leads Sema4’s development of predictive models for complex human diseases. He is also an Associate Professor at the Icahn School of Medicine at Mount Sinai in the Department of Genetics & Genomic Sciences and Institute for Data Science & Genomic Technology.
Ke’s research focuses on the genetic and environmental basis of human diseases, using translational statistical genetics and computational algorithms to mine massive datasets and deliver clinical insights.
Chief Information Security Officer
In his role as Chief Information Security Officer, Shay Hassidim helps Sema4 implement its information technology, healthcare intelligence platform, and other clinical systems using cloud-based architecture.
Shay has more than two decades of experience in technical management and leadership skills and has been involved in large-scale projects with multiple Fortune 500 multinational global companies. Prior to joining Sema4, Shay was part of the GigaSpaces XAP and Cloudify product leadership teams from their inception, served as a Lead Architect and Technical Manager at Versant ODBMS, and held the role of VMDB Database Tools Lead Architect at Sirius Technologies.
Shay holds a B.Sc. in Electrical and Computer Engineering from Ben-Gurion University of the Negev in Israel, and has in-depth technical experience with diverse technologies, including cloud computing, in-memory computing, and big data.
VP, Clinical Informatics
As VP, Clinical Informatics, at Sema4, Li Li, M.D., leads research focused on developing a common data model for electronic medical records, driving the development and improvement of clinical applications in areas including reproductive disease and newborn health. She has published extensively in the fields of precision medicine, bioinformatics, and clinical bioinformatics, with more than 75 peer-reviewed papers in leading journals.
Li is also an Assistant Professor at the Icahn School of Medicine at Mount Sinai in the Department of Genetics & Genomic Sciences and the Institute for Next Generation Healthcare. She is trained as both a physician and bioinformatician, with an M.D. in Clinical Medicine from the Dalian Medical School in China and an M.S. in Bioinformatics from Boston University, and has over 16 years of experience in industry and academia.
Chief Compliance and Privacy Officer
As Sema4’s Chief Compliance and Privacy Officer, Murali Mani is responsible for ensuring trust and transparency with patients, partners, and investors, driving policy, certifications and conducting audits to comply with key regulations, standards, and certifications.
Prior to joining Sema4 in 2020, Murali was the Director of Compliance covering privacy, security, and data governance at IBM Watson Health, where he built a quality and compliance program for an extensive portfolio of health products and services in more than ten countries. He also served as the Senior Privacy Officer for Philips Group Innovation, with responsibility for overseeing several hundred human subject studies across approximately a dozen countries.
Murali has a Ph.D. in Mechanical Engineering from Northwestern University. He also holds Certified Information Privacy Professional (CIPP) and Certified Information Privacy Manager (CIPM) credentials from the International Association of Privacy Professionals,and Project Management Professional (PMP) credentials from the Project Management Institute.
VP, Technology Development
Robert (Bobby) Sebra, Ph.D., leads Technology Development at Sema4 with a focus on technology adoption and the creation of high-throughput diagnostics. He is a leading expert in sequencing platforms and a pioneer in single molecule and single cell assay development.
Robert has published more than 150 papers in top tier journals, including Science, Cell, Nature, and The New England Journal of Medicine, and his work has led to multiple issued patents. He also serves as the Director of Technology Development at the Icahn Institute of Genomics & Multiscale Biology and an Associate Professor in the Department of Genetics & Genomic Sciences at the Icahn School of Medicine at Mount Sinai.