Rong Chen, PhD, is an expert in translational bioinformatics. Rong has over 20 years of experience developing bioinformatics databases, methods, software, and platforms to drive clinical and research applications in the academic, software, diagnostic, and biotech industries. He has published more than 110 papers in journals such as Nature Biotechnology and The Lancet.
As Chief Health Informatics Officer, Rong leads Sema4’s informatics teams that are responsible for the structuring and management of genomic- and health-related data with health system partners, as well as the development of a health insight platform to engage researchers, clinicians, and administrators to improve the standard of care, an artificial intelligence platform to engage biopharma scientists for advanced analytics, and a genomic platform to scale up genetic testing.
Before joining Sema4, Rong was an Assistant Professor in the Department of Genetics & Genomic Sciences and Institute of Genomics & Multiscale Biology, and Director of the Clinical Genome Informatics Laboratory at Icahn School of Medicine at Mount Sinai.
Rong received his BS in Chemical Physics from the University of Science and Technology in China, his MS in Structural Biology from the Chinese Academy of Sciences, and his PhD in Bioinformatics from Boston University.
Chief Medical Officer – Reproductive Health
In addition to serving as Chief Medical Officer – Reproductive Health at Sema4, Alan B. Copperman, MD, is co-founder and a Medical Director of RMA of New York, one of the country’s largest and most prestigious IVF centers. He also serves as the Director of the Division of Reproductive Endocrinology & Infertility and the Vice-Chairman of the Department of Obstetrics, Gynecology & Reproductive Science at Icahn School of Medicine at Mount Sinai.
Alan has published numerous papers, book chapters, and abstracts on reproductive medicine and is frequently featured in print, digital media, and local and national news shows. He has been named to New York Magazine’s list of Best Doctors for 16 years in a row and has been recognized annually by Castle Connolly and SuperDocs as one of the top fertility doctors.
Head of Statistical Genomics
Ke Hao, ScD, leads Sema4’s development of predictive models for complex human diseases. He is also a Professor at the Icahn School of Medicine at Mount Sinai in the Department of Genetics & Genomic Sciences.
Ke’s research focuses on the genetic and environmental basis of human diseases, using translational statistical genetics and computational algorithms to mine massive datasets and deliver clinical insights.
Chief Information Security Officer
In his role as Chief Information Security Officer, Shay Hassidim helps Sema4 implement its information technology, healthcare intelligence platform, and other clinical systems using cloud-based architecture.
Shay has more than two decades of experience in technical management and leadership skills and has been involved in large-scale projects with multiple Fortune 500 multinational global companies. Prior to joining Sema4, Shay was part of the GigaSpaces XAP and Cloudify product leadership teams from their inception, served as a Lead Architect and Technical Manager at Versant ODBMS, and held the role of VMDB Database Tools Lead Architect at Sirius Technologies.
Shay holds a BSc in Electrical and Computer Engineering from Ben-Gurion University of the Negev in Israel, and has in-depth technical experience with diverse technologies, including cloud computing, in-memory computing, and big data.
SVP, Clinical Informatics
As SVP, Clinical Informatics, at Sema4, Li Li, MD, leads research focused on developing a common data model for electronic medical records, driving the development and improvement of clinical applications in areas including reproductive disease and newborn health. She has published extensively in the fields of precision medicine, bioinformatics, and clinical bioinformatics, with more than 90 peer-reviewed papers in top journals such as Nature Biotech, Science Translational Medicine, Journal of Clinical Investigation, PNAS, etc.
Li is also an Adjunct Assistant Professor at the Icahn School of Medicine at Mount Sinai in the Department of Medicine. She is trained as both a physician and bioinformatician, with an MD in Clinical Medicine from the Dalian Medical School in China and an MS in Bioinformatics from Boston University, as well as over 16 years of experience in industry and academia.
Chief Compliance and Privacy Officer
As Sema4’s Chief Compliance and Privacy Officer, Murali Mani is responsible for ensuring trust and transparency with patients, partners, and investors, driving policy and certifications and conducting audits to comply with key regulations, standards, and certifications.
Prior to joining Sema4 in 2020, Murali was the Director of Compliance covering privacy, security, and data governance at IBM Watson Health, where he built a quality and compliance program for an extensive portfolio of health products and services in more than ten countries. He also served as the Senior Privacy Officer for Philips Group Innovation, with responsibility for overseeing several hundred human subject studies across approximately a dozen countries.
Murali has a PhD in Mechanical Engineering from Northwestern University. He also holds Certified Information Privacy Professional (CIPP) and Certified Information Privacy Manager (CIPM) credentials from the International Association of Privacy Professionals,and Project Management Professional (PMP) credentials from the Project Management Institute.
Qi Pan, PhD, has over 16 years of experience in biotech and pharmaceutical Research & Development (R&D), with an in-depth knowledge of oncology and biotherapeutic drug discovery and development. Qi serves as Senior Vice President of Research and is responsible for driving the next wave of research-led advances to augment our competitive edge with our healthcare systems and pharma partners, as well as delivering high priority research projects. She was promoted to her current role from Vice President in 2020.
Prior to Sema4, Qi was Vice President of R&D at Legend Biotech, a leading biotech company, overseeing the discovery of innovative CAR-T therapy to treat cancer. Prior to that, Qi worked at leading pharmaceutical companies, including Genentech and Boehringer Ingelheim, on biotherapeutics discovery.
Qi received her PhD from Harvard University in the field of molecular and cellular biology.
VP, Technology Development
Robert (Bobby) Sebra, PhD, leads Technology Development at Sema4 with a focus on technology adoption and the creation of high-throughput diagnostics. He is a leading expert in sequencing platforms and a pioneer in single molecule and single cell assay development.
Robert has published more than 150 papers in top tier journals, including Science, Cell, Nature, and The New England Journal of Medicine, and his work has led to multiple issued patents. He also serves as the Director of Technology Development at the Icahn Institute of Genomics & Multiscale Biology and an Associate Professor in the Department of Genetics & Genomic Sciences at the Icahn School of Medicine at Mount Sinai.