Screening today for a healthier tomorrow

With one of the most comprehensive and accurate Expanded Carrier Screens available, we are committed to helping patients make informed family planning decisions for a healthier future.


Why should I choose Sema4 Expanded Carrier Screen?

If you are pregnant or planning for pregnancy, our Expanded Carrier Screen is designed to give you a comprehensive and accurate understanding of your risk of passing a genetic condition onto your child.


With a simple blood or saliva test, find out if you and your partner are carriers of genetic variants (or changes) that could affect your children. Saliva tests can also be taken remotely during the COVID-19 outbreak.


Sema4 Expanded Carrier Screen is a comprehensive carrier screen for more than 280 inherited diseases to give you the information you need to plan for a healthier future for your family.


When assessing your risk, precision matters. Our Expanded Carrier Screen uses advanced sequencing technologies for results that are >95% accurate.

How does it work?

To get started, talk to your doctor about requesting the screen.

Your doctor takes a single blood draw or saliva sample and sends it to our lab. Saliva tests can also be taken remotely during the COVID-19 outbreak.

Your sample is analyzed by our state-of-the-art sequencing technologies. This usually takes about 2 weeks.

Once your genetic screen is completed, a genetic counselor may contact you to explain your results and answer any questions you might have.

Can carrier screening be customized?

Yes. While a comprehensive carrier screen is recommended if you are pregnant or planning for pregnancy, carrier screening with Sema4 can also be customized for your unique family planning needs. For more information, please visit our FAQ page.

Learn more with our Carrier Screening Pre-Test Video

Your healthcare provider may have discussed the option of genetic carrier screening with you. The purpose of genetic carrier screening is to determine if a reproductive couple may be at increased risk of having a child affected with a genetic condition. Watch this informational video to learn more about genetics and the possible outcomes of carrier screening.

Additional Resources


Looking to register your Saliva Kit? Registration of your Carrier Screening Saliva Kit is no longer necessary due to our upgraded tracking system. Please move to the next step listed on your instruction sheet.


What’s coming soon

We will soon launch Expanded Carrier Screen with Personalized Residual Risk. This advanced carrier screening will offer analysis of up to 502 genes and utilizes proprietary technology to identify a patient’s molecular ancestry on a genome-wide level for tailored, personalized residual risk. Such information is critical for providers to better understand a patient’s chance for passing on inherited disease and further builds on Sema4’s gold standard Expanded Carrier Screen.


View our Coming Soon Flyer


How Can We Help You?

Are you interested in learning more? Reach out using the form below.