Comprehensive Common Cancer Panel
Test code: GDB275
Related gene(s): APC, ATM, AXIN2, BAP1, BARD1, BMPR1A, BRCA1, BRCA2, BRIP1, CDH1, CDK4, CDKN2A, CHEK2, CTNNA1, EPCAM, FANCC, FANCM, FH, FLCN, HOXB13, MET, MITF, MLH1, MSH2, MSH3, MSH6, MUTYH, NBN, NF1, NTHL1, PALB2, PMS2, POLD1, POLE, POT1, PTEN, RAD51C, RAD51D, RECQL, SCG5 (GREM1), SDHB, SDHC, SDHD, SMAD4, STK11, TP53, TSC1, TSC2, VHL
The Comprehensive Panel is a way to evaluate multiple hereditary cancer conditions in an individual. This panel includes genes associated with hereditary cancers across the major organ systems including breast, endometrial, colon, pancreatic, prostate, renal, brain, and others.
- Colorectal Cancer
- Familial Adenomatou Polyposis (FAP)
- Pancreatic Cancer
- Breast Cancer
- Endometrial Cancer
- Ovarian Cancer
- Attenuated Familial Adenomatous Polyposis (AFAP)
- Cancer at a young age, such as breast, colon, or renal cancer
- Multiple cancers in one person, either of the same origin (such as two separate colon cancers) or of different origins (such as breast cancer and ovarian cancer)
- Diagnosis of certain rare cancers, such as ovarian or male breast cancer
- Multiple relatives diagnosed with the same or related cancers on the same side of the family and spanning multiple generations
- Deletion/duplication analysis
- Next-Gen sequencing
- Preferred: 2-5 mL Blood – Lavender Top Tube
- Alternative: Buccal Swabs, Fibroblasts (separate charge for cell culture may apply)
- CPT code(s):* 81433×1, 81432×1 (HBOC diagnosis); 81435×1, 81436×1 (non-HBOC diagnosis)
- Turnaround Time:** 2 weeks
*The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
**Reporting times are typical and begin once the sample(s) are received at the GeneDx laboratory, but could be extended in situations outside GeneDx’s reasonable control.