Epilepsy Pharmacogenetic Genotyping Panel


Related Gene(s): ABCG2, COMT, CYP2B6, CYP2C9, CYP2C19, CYP2D6, GRIK4, OPRM1, UGT2B15

Related Medication(s): Please see the Pharmacogenetic Medication and Gene Panels table for further information

Our Epilepsy Pharmacogenetic Genotyping Panel is designed to detect allelic and copy number variants in 9 drug response genes that are clinically actionable or informative on 51 medications. This test is intended to help physicians make therapeutic decisions for these selected medications that are indicated for patients with epilepsy and which can have interindividual response variability.

For this test, targeted genotyping of functional sequence variants is performed using the Agena Biosciences platform and copy number variants interrogated for the CYP2B6, CYP2C9, CYP2C19, and CYP2D6 genes by MLPA.


Specimen Requirements

  • Blood: One 5-10 mL ACD tube (yellow top) and two 5-10 mL EDTA tubes (lavender top)
  • Saliva: Saliva specimens are accepted in Oragene DNA (OG-500) kits by DNA Genotek

Ordering Information

Shipping

  • Ship at room temperature

Turnaround Time

  • 10-14 days from receipt of specimen


Resources

General Genetic Test Requisition
Epilepsy Pharmacogenetic Genotyping Panel Clinical Information Sheet