Oncology Pharmacogenetic Genotyping Panel
Related Gene(s): CYP2C8, CYP2D6, DPYD, G6PD, NUDT15, UGT1A1, TPMT
Related Medication(s): Please see the Pharmacogenetic Medication and Gene Panels table for further information
Our Oncology Pharmacogenetic Genotyping Panel is designed to detect allelic and copy number variants in 7 drug response genes that inform on 15 medications. This test is intended to help physicians make therapeutic decisions for these selected medications that are indicated for patients with certain cancers and which can have with interindividual response variability.
For this test, targeted genotyping of functional sequence variants is performed using the Agena Biosciences platform and copy number variants interrogated for the CYP2C8 and CYP2D6 genes by MLPA. In addition, the UGT1A1*28 dinucleotide repeat allele is genotyped by PCR and capillary electrophoresis.
Specimen Requirements
- Blood: One 5-10 mL ACD tube (yellow top) and two 5-10 mL EDTA tubes (lavender top)
- Saliva: Saliva specimens are accepted in Oragene DNA (OG-500) kits by DNA Genotek
Ordering Information
Shipping
- Ship at room temperature
- Ship to:
Sema4
62 Southfield Ave, Stamford, CT 06902
Phone: 800-298-6470 / Fax: 646-859-6870
Turnaround Time
- 10-14 days from receipt of specimen
Related Tests
- Cardiovascular Pharmacogenetic Genotyping Panel
- Comprehensive Pharmacogenetic Genotyping Panel
- Epilepsy Pharmacogenetic Genotyping Panel
- Pain Pharmacogenetic Genotyping Panel
- Pediatric Pharmacogenetic Genotyping Panel
- Psychiatric Pharmacogenetic Genotyping Panel
- Targeted Pharmacogenetic Genotyping Panel
Resources
General Genetic Test Requisition
Oncology Pharmacogenetic Genotyping Panel Clinical Information Sheet
