Orotic Acid, Urine

 

Quantitative urinary orotic acid analysis is used in the evaluation of patients with hyperammonemia and a suspected urea cycle defect (UCD). It is typically ordered in conjunction with plasma amino acids and urine organic acids. Urine orotic acid is also used in conjunction with plasma amino acids when monitoring patients with UCD. This test can also detect rare inherited orotic acidurias with pyrimidine defects. Orotic acid is measured by gas chromatography and mass spectrometry (GC/MS) method.


Specimen Requirements

  • Urine: 5-10 mL (random or preferably morning first void) in a clean container without preservatives, then freeze

Ordering Information

Shipping

  • Ship overnight frozen on dry ice
  • Ship to:
    Sema4
    62 Southfield Ave, Stamford, CT 06902
    Phone: 800-298-6470 / Fax: 646-859-6870

 

Turnaround Time

  • Routine: 5 days

 


Resources

Biochemical Genetic Testing Requisition