Melanoma Panel

Test code: GDB399

Related gene(s): BAP1, BRCA2, CDK4, CDKN2A, MITF, POT1, PTEN, RB1, TP53

Test description:

The Melanoma Panel includes genes associated with increased lifetime risk of developing melanoma. While most of the genes included in this panel have management guidelines published, there are some with emerging evidence to support association with cancer predisposition. This panel can provide information that may help healthcare providers and patients make more informed medical decisions and lifestyle choices.

Conditions:

  • Familial Cutaneous Malignant Melanoma

 
Clinical utility:

  • Identification of a hereditary susceptibility to malignant melanoma
  • Development of a clinical surveillance plan for early detection
  • Identification of at-risk family members

 
Lab method:

  • Deletion/duplication analysis
  • Next-Gen sequencing

Specimen Requirements

  • Preferred: 2-5 mL Blood – Lavender Top Tube
  • Alternative: Buccal Swabs, Fibroblasts (separate charge for cell culture may apply)

Ordering Information

  • CPT code(s):* 81404×1, 81479×1
  • Turnaround Time:** 2 weeks


*The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
**Reporting times are typical and begin once the sample(s) are received at the GeneDx laboratory, but could be extended in situations outside GeneDx’s reasonable control.


Resources

Hereditary Cancer Requisition
Hereditary Cancer Re-requisition
GeneDx Test Information Sheet (TIS)