Renal Cancer Panel

 
Test code: GDB394

Related gene(s): BAP1, EPCAM, FH, FLCN, MET, MITF, MLH1, MSH2, MSH6, PMS2, PTEN, SDHB, SDHC, SDHD, TP53, TSC1, TSC2, VHL

Test description:

The Renal Cancer Panel includes genes associated with increased lifetime risk of developing renal cancer. These individuals are also at risk of developing renal cancer at an earlier age compared to the general population.

Conditions:

  • Renal Cancer

 
Clinical utility:

  • A personal or family history of renal cancer at a young age (i.e. ≤46 years)
  • A personal or family history of bilateral renal cancer (disease in both kidneys) or multiple primary tumors in a single kidney
  • Multiple renal cancers within a family
  • A pattern of cancer in which the individuals with similar or related cancers (see table below) are on one side of the family spanning multiple generations

 
Lab method:

  • Deletion/duplication analysis
  • Next-Gen sequencing

Specimen Requirements

  • Preferred: 2-5 mL Blood – Lavender Top Tube
  • Alternative: Buccal Swabs, Extracted DNA

Ordering Information

  • CPT code(s):* 81403×1, 81404×1, 81405×1, 81406×1, 81407×1
  • Turnaround Time:** 3 weeks


*The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
**Reporting times are typical and begin once the sample(s) are received at the GeneDx laboratory, but could be extended in situations outside GeneDx’s reasonable control.


Resources

Hereditary Cancer Requisition
Hereditary Cancer Re-requisition
GeneDx Test Information Sheet (TIS)